Selected Publications:
Dopamine neuron-specific LRRK2 G2019S effects on gene expression revealed by translatome profiling. Pallos, J., Jeng, S.,
McWeeney, S., Martin, I. (2021) Neurobiology of Disease, In Press.
Chittoor-Vinod, V.G., Villalobos-Cantor, S., Roshak, H., Shea, K., Abalde-Atristain, L. and Martin, I. (2020). Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson’s Disease Models. Journal of Neuroscience, 40(32) 6234-6249.
Kim, J.K., Yin, X., Jhaldiyal, A., Kahn, M.R., Martin, I., Xie, Z., Perez-Rosello, T., Kumar, M., Abalde-Atristain, L., Xu, J., Chen, L., Eacker, S.M., Surmeier, S.M., Ingolia, N.T., Dawson, T.M. and Dawson, V.L. (2020). Defects in mRNA translation in LRRK2-mutant hiPSC-derived dopaminergic neurons leads to dysregulated calcium homeostasis. Cell Stem Cell, 27(4) 633-645.
Lavoy, S., Chittoor-Vinod, V.G., Chow, C.Y., Martin, I. (2018) Genetic Modifiers of Neurodegeneration in a Drosophila Model of Parkinson's Disease. Genetics, 209(4) 1345-1356.
Martin, I. (2017) Resveratrol for Alzheimer's disease? Science Translational Medicine 1;9(375) pii
Martin, I. (2016) Alzheimer's medicine: β-Amyloid takes a siP. Science Translational Medicine, 14;8(369) 369.
Kim, J.W., Abalde-Atristain, L., Jia, H., Martin, I., Dawson, V.L., Dawson, T.M. (2016) Protein translation in Parkinson’s disease. In: Verstreken P, eds. Parkinson’s Disease: Molecular Mechanisms Underlying Pathology. San Diego, CA: Elsevier.
Martin, I., Chittoor, V.G. (2016) Parkinson disease: Insect screens for PD therapies - keep the flies in. Nature Reviews Neurology, 12(6) 318-319.
Martin, I. (2016) Decoding Parkinson’s Disease Pathogenesis: The Role of Deregulated mRNA Translation. Journal of Parkinson’s Disease, 6(1) 17-27.
Karuppagounder, S.S., Xiong, Y., Lee, Y., Lawless, M.C., Kim, D., Nordquist, E., Martin, I., Ge, P., Brahmachari, S., Jhaldiyal, A., Kumar, M., Andrabi, S.A., Dawson, T.M., Dawson, V.L. (2016) LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity. Journal of Chemical Neuroanatomy, 76(Pt B) 90-97.
Martin, I., Kim, J.W., Lee, B.D., Kang, H., Xu, J-C., Jia, H., Stankowski, J., Kim, M-S., Zhong, J., Kumar, M., Andrabi, S.A., Xiong, Y., Dickson, D.W., Wszolek, Z.K., Pandey, A., Dawson, T.M., Dawson, V.L. (2014) Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson’s disease. Cell, 157(2) 472-485.
Highlighted in Cell, 157(2) 291-293.
Highlighted in ACS Chemical Biology, 9(5) 1067-1069.
Highlighted in Movement Disorders, 29(8) 990.
Highlighted in ASBMB News, October 2014
Martin, I., Abalde-Atristain, L., Kim, J.W., Dawson, T., Dawson, V.L. (2014) Aberrant Protein Synthesis in G2019S LRRK2 Drosophila Parkinson’s Disease-Related Phenotypes. Fly, 8(3) 165-169.
Martin, I., Kim, J.W., Dawson, V.L., Dawson, T. (2014) LRRK2 Pathobiology in Parkinson’s Disease. Journal of Neurochemistry, 131(5) 554-565.
Martin, I., Dawson, V.L., Dawson, T.M. (2011) Recent advances in the genetics of Parkinson's disease. Annual Review of Genomics and Human Genetics, vol 22 p301-325.
Martin, I., Dawson, V.L. and Dawson, T.M. (2010) The Impact of Genetic Research on Our Understanding of Parkinson’s Disease. Progress in Brain Research, vol 183, p21-41. editors Anders Björklund and M. Angela Cenci.
Dopamine neuron-specific LRRK2 G2019S effects on gene expression revealed by translatome profiling. Pallos, J., Jeng, S.,
McWeeney, S., Martin, I. (2021) Neurobiology of Disease, In Press.
Chittoor-Vinod, V.G., Villalobos-Cantor, S., Roshak, H., Shea, K., Abalde-Atristain, L. and Martin, I. (2020). Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson’s Disease Models. Journal of Neuroscience, 40(32) 6234-6249.
Kim, J.K., Yin, X., Jhaldiyal, A., Kahn, M.R., Martin, I., Xie, Z., Perez-Rosello, T., Kumar, M., Abalde-Atristain, L., Xu, J., Chen, L., Eacker, S.M., Surmeier, S.M., Ingolia, N.T., Dawson, T.M. and Dawson, V.L. (2020). Defects in mRNA translation in LRRK2-mutant hiPSC-derived dopaminergic neurons leads to dysregulated calcium homeostasis. Cell Stem Cell, 27(4) 633-645.
Lavoy, S., Chittoor-Vinod, V.G., Chow, C.Y., Martin, I. (2018) Genetic Modifiers of Neurodegeneration in a Drosophila Model of Parkinson's Disease. Genetics, 209(4) 1345-1356.
Martin, I. (2017) Resveratrol for Alzheimer's disease? Science Translational Medicine 1;9(375) pii
Martin, I. (2016) Alzheimer's medicine: β-Amyloid takes a siP. Science Translational Medicine, 14;8(369) 369.
Kim, J.W., Abalde-Atristain, L., Jia, H., Martin, I., Dawson, V.L., Dawson, T.M. (2016) Protein translation in Parkinson’s disease. In: Verstreken P, eds. Parkinson’s Disease: Molecular Mechanisms Underlying Pathology. San Diego, CA: Elsevier.
Martin, I., Chittoor, V.G. (2016) Parkinson disease: Insect screens for PD therapies - keep the flies in. Nature Reviews Neurology, 12(6) 318-319.
Martin, I. (2016) Decoding Parkinson’s Disease Pathogenesis: The Role of Deregulated mRNA Translation. Journal of Parkinson’s Disease, 6(1) 17-27.
Karuppagounder, S.S., Xiong, Y., Lee, Y., Lawless, M.C., Kim, D., Nordquist, E., Martin, I., Ge, P., Brahmachari, S., Jhaldiyal, A., Kumar, M., Andrabi, S.A., Dawson, T.M., Dawson, V.L. (2016) LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity. Journal of Chemical Neuroanatomy, 76(Pt B) 90-97.
Martin, I., Kim, J.W., Lee, B.D., Kang, H., Xu, J-C., Jia, H., Stankowski, J., Kim, M-S., Zhong, J., Kumar, M., Andrabi, S.A., Xiong, Y., Dickson, D.W., Wszolek, Z.K., Pandey, A., Dawson, T.M., Dawson, V.L. (2014) Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson’s disease. Cell, 157(2) 472-485.
Highlighted in Cell, 157(2) 291-293.
Highlighted in ACS Chemical Biology, 9(5) 1067-1069.
Highlighted in Movement Disorders, 29(8) 990.
Highlighted in ASBMB News, October 2014
Martin, I., Abalde-Atristain, L., Kim, J.W., Dawson, T., Dawson, V.L. (2014) Aberrant Protein Synthesis in G2019S LRRK2 Drosophila Parkinson’s Disease-Related Phenotypes. Fly, 8(3) 165-169.
Martin, I., Kim, J.W., Dawson, V.L., Dawson, T. (2014) LRRK2 Pathobiology in Parkinson’s Disease. Journal of Neurochemistry, 131(5) 554-565.
Martin, I., Dawson, V.L., Dawson, T.M. (2011) Recent advances in the genetics of Parkinson's disease. Annual Review of Genomics and Human Genetics, vol 22 p301-325.
Martin, I., Dawson, V.L. and Dawson, T.M. (2010) The Impact of Genetic Research on Our Understanding of Parkinson’s Disease. Progress in Brain Research, vol 183, p21-41. editors Anders Björklund and M. Angela Cenci.
